From 1466 Florentine merchant-bankers and gentlemen active in the city of Lyon assigned the church of Notre-Dame de Confort as the seat of their spiritual life and of their collective and private patronage. The scanty French sources and the enormous material losses – from the Huguenot violence of 1562 to the destruction of the building in 1816 – have made the reconstruction of these transnational artistic commissions difficult. A file kept in the Florence State Archive provides illuminating information on the chapel founded by Bartolomeo di Francesco Panciatichi, for which the 'Assumption' by Andrea del Sarto, now in the Galleria Palatina in Florence, was intended.