This article examines an unpublished miniature signed by the painter Ettore Sampaolo and dated June 2, 1882. The parchment is inserted in an album commissioned by the citizens of Sansepolcro and kept in the Museo Centrale del Risorgimento in Rome. The album is dedicated to Giuseppe Garibaldi on the first anniversary of his death (1883). The image shows seven medallions with famous men of Sansepolcro: Piero della Francesca in the center and around him, from above, the painter Santi di Tito, the mathematician Luca Pacioli, Giovanni dalle Bande Nere's lieutenant Giovanni Turini, the military engineer and cartographer Giovan Francesco Cantagallina, the painter and engraver Cherubino Alberti and finally thebrave captain Carlo Graziani. The figures are surrounded by a rich grotesque decoration. The choice to portray famous men is part of a very widespread illustrative taste in the Italian peninsula in the second half of the 19th century, but the iconographies adopted by Sampaolo reveal themselves, as in the case of Luca Pacioli, to be very peculiar. In the municipal deposits of Sansepolcro six round paintings are preserved of which five reproduce the same figures and the same iconographies of the parchment; therefore the problem of the attribution to Sampaolo himself and of the chronological relationship between the two works arises.